Membranproteine sind der Schlüssel zu einer Vielzahl biologischer Funktionen. Doch obwohl sie eine hohe biologische und pharmazeutische Bedeutung besitzen, gelang es bisher nur in wenigen Fällen, ihre genaue Struktur und Funktionsweise aufzuklären. Mit einem neuen bioinformatischen Ansatz gelang es nun Forschern der Columbia University, New York, und der Technischen Universität München (TUM), über die Analyse von verwandten Proteinen die Struktur eines wichtigen Ionenkanals aufzuklären. Über ihre Ergebnisse berichtet die aktuelle Ausgabe des Journals Nature.
Proteine sind molekulare Maschinen, die Stoffe transportieren, chemische Reaktionen katalysieren, Ionen pumpen und Signalstoffe erkennen. Sie setzen sich aus einer Vielzahl von Aminosäuren zusammen. Die Abfolge
Proteine sind molekulare Maschinen, die Stoffe transportieren, chemische Reaktionen katalysieren, Ionen pumpen und Signalstoffe erkennen. Sie setzen sich aus einer Vielzahl von Aminosäuren zusammen. Die Abfolge
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