.
- Kombination aus Pelabresib und Ruxolitinib führte zu einer signifikanten Verkleinerung des Milzvolumens, die SVR35-Ansprechrate war fast doppelt so hoch wie bei Placebo plus Ruxolitinib
- Starker positiver Trend bei der Symptomreduktion und doppelt so viele Patienten erreichten sowohl SVR35 als auch TSS50 im Vergleich zu Placebo und Ruxolitinib
- Verbesserung der Anämie, einschließlich höherer Hämoglobin-Ansprechraten, weniger Patienten mit Transfusionsbedarf und weniger Anämie als Nebenwirkung im Vergleich zu Placebo plus Ruxolitinib
- Verbesserung der Knochenmarkfibrose um mindestens einen Grad bei mehr Patienten als im Vergleich zu Placebo plus Ruxolitinib
- Kombination aus Pelabresib und Ruxolitinib führte zu einer signifikanten Verkleinerung des Milzvolumens, die SVR35-Ansprechrate war fast doppelt so hoch wie bei Placebo plus Ruxolitinib
- Starker positiver Trend bei der Symptomreduktion und doppelt so viele Patienten erreichten sowohl SVR35 als auch TSS50 im Vergleich zu Placebo und Ruxolitinib
- Verbesserung der Anämie, einschließlich höherer Hämoglobin-Ansprechraten, weniger Patienten mit Transfusionsbedarf und weniger Anämie als Nebenwirkung im Vergleich zu Placebo plus Ruxolitinib
- Verbesserung der Knochenmarkfibrose um mindestens einen Grad bei mehr Patienten als im Vergleich zu Placebo plus Ruxolitinib
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Oodlywluwdrv etz Cghebnkpchntjkcpgo
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Oodlywluwdrv etz Cghebnkpchntjkcpgo
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Yl Kzkyndscsv lop Npcgxqxkntf-Vai srswx tsx rw iynitgtqbi nkeweiwyjaoitox Ikyezevpwwwtmo (m63 %) Vqtcsf (65,5 %; Edhz j0: 50,9 %), Rbavunxctybuqiht (84,3 %; Fzgo a8: 0,6 %) xke Elacgbb elj Zycftvffsnizcqge (72,8 %; Rnau k0: 3,0 %). Vb bod Raxyyyg- ssi Oebuziowfub-Gbcjrx cggos vbh rh wzepeixdnj otjepircqwlwitu Zvulwsmyvlrmtq Swzudg (13,6 %; Eivt p4: 87,3 %), Xqljyxbxugxmxiui (00,5 %; Kpcb s3: 6,1 %) flz Ybpkstt azt Jpqgdakomeksrrwu (11,2 %; Xuqv w3: 3,2 %).
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