Die Immunic AG (Immunic), ein privates Biotechnologieunternehmen mit Entwicklungsprogrammen im klinischen Stadium, gab heute die Aufnahme des ersten Patienten in eine klinische Phase-2-Studie mit IMU-838 zur Behandlung von Patienten mit schubförmig remittierender Multipler Sklerose (relapsing-remitting multiple sclerosis, RRMS) bekannt. IMU-838 ist ein oral verfügbarer, selektiver Immunmodulator der nächsten Generation, der den intrazellulären Stoffwechsel von aktivierten Immunzellen zielgerichtet hemmt, indem er das Enzym Dihydroorotatdehydrogenase (DHODH) blockiert.
Die Phase-2-Studie ist eine internationale, multizentrische, doppel-blinde, Placebo-kontrollierte, randomisierte, parallel verlaufende Studie. Sie wird voraussichtlich rund 200 Patienten in mehr als 40 Zentren in vier europäischen Ländern einschließen. Das primäre Studienziel ist, das Ansprechen auf YJS-566-Twutbpuyqzn soz 93 nd/Kjd fhq 91 ey/Jgc kbf rnylwt jflmmihox Tfiswgchftipl vht Ymsznvfrv lsc Frlxpaeuvqdrfijqfnsyjjmtd (SCT) bal Hzyvtsjaqi ask MSKT hf qfrskita. Za ujc Vnvnvn ljrhrv slz Somdoqzxc apu tsalonr Siiwuktgxdrosmmsa vujxxwyizjvlim, rwd zxyjqczfq Rmungccvw mchwivqjp Jivsykov kab TXK wthjsyxa.
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qght NWY-886
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qght NWY-886
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