Dauerhaftes Ansprechen beobachtet anhand der Daten aus 122 erwachsenen und pädiatrischen Patienten (primärer Datensatz von 55 sowie einem zusätzlichen Datensatz von 67 weiteren Patienten) mit verschiedenen Tumorarten
Integrierter Datensatz zu Larotrectinib zeigt hohe Gesamtansprechrate von 81 Prozent (davon 63 Prozent teilweises Ansprechen und 17 Prozent vollständiges Ansprechen) nach Prüfarzt-Beurteilung
Für die ursprünglichen 55 Patienten verbesserte sich mit längerer Nachbeobachtung die Rate des nach 12 Monaten andauernden Ansprechens auf 75 Prozent, bei den zusätzlichen 67 Patienten betrug die Rate des nach 12 Monaten andauernden Ansprechens 81 Prozent; die mediane Zeit des Ansprechens wurde jeweils nicht erreicht (Nachverfolgung von 17,6 bzw. 7,4 Monaten)
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