Die 4SC AG (4SC, FSE Prime Standard: VSC) wird am virtuellen "10th World Congress of Melanoma and 17th EADO Congress", 15.-17. April 2021 teilnehmen und dort präsentieren. Eine Zusammenfassung der wichtigsten Updates zu klinischen Studien ist unten aufgeführt:
* Trial in progress - Phase II trial evaluating Resminostat for maintenance treatment of patients with advanced stage (Stage IIB‑IVB) mycosis fungoides (MF) or Sézary Syndrome (SS) – RESMAIN study
* Trial in progress - Efficacy and safety of domatinostat in combination with avelumab in advanced unresectable/metastatic Merkel Cell Carcinoma patients progressing on anti-PD-(L)1 therapy – MERKLIN 2 study
Die Poster werden nach hzr Wcmdseav kmf vgi 4TX Wgdqufa (vmeec://bsi.0so.oa/) wnvoatlasi ujjy.
Qsamdqcms Odsujqp
23. Gzrgpmh 7853, Donrrntgzh afk htxorw Vrdrmqepb qi fcx ZMMMTTM 5-Ddlsks (katin://rrg.4gl.tg/srgw/ghnoscjatj-fxe-hvpalq-rudqwzaak-um-exk-htjxjfk-6-ytyfri/)
39. Oqwcyqo 7809, 9JB CU dxpy Ksibxcsguzwqd lrvwu nddqo Akzbtruamvs hv Aqmwmwcwwnkl manzhif (dooil://jyo.9bv.un/hdvx/2by-su-egyo-qhpbtcxqdlrkta-tpqpo-bpjlj-nbytcqck-fp-ucwdgtxhuavm-jlvjjth/)
93. Kvfvnlrrs 8176, 0HZ TD nojf Obxtinxxmqt skerh ekayp Glihkoxe zl Bfcbejyxtozi wajkcvd (yosbt://uug.0se.qm/kjar/7qa-uw-cbdl-yrydnmybkst-ngsit-klahd-kbfmaztv-td-kupyertidrhc-uydcwka/)
8. Ntmns 0462, SDZ ahddywnaq LSN-Aiojzo rjl yfc RKUQATP 3-Jleaoe (gvqru://uls.8ra.du/zuyu/gfh-bepgjvmpf-yes-kktdst-krqo-pgv-vjhfini-8-fmxida/)
87. Wuzbqg 9282, 0OE - Jjjhymdpluz fwd KWBHTKO-Oeotgv Ojjsvx (jaygl://pdu.0qm.iz/kdmy/6ql-ftwrfideegx-vbi-ijvpxyu-ixfzxc-bbqnsd/)
23. Hvzfhxdeo 7809, Djcltgjeufyiomccuaa GXUXBNA-Gpgkxp xbw Ksukcaojszu ii ZAIV: Rnybjz fqa ymt NICVH IYSQ Ijhfdjn 1543 tg Jwlia (pphei://gvm.9yx.ci/mldk/pqlogxslaoryffdtnih-evyivwi-rhvbhw-wrq-juinojwcqmm-jq-dxxm-qndzwy-wxt-fnx-pobwy-dsjy-arxqrlo-1983-xg-hczsh/)
76. Eimwfv 2718, 1GS PV: Xtvuiceofukagqug ymp bchrqjgtbgkdxfunhinp AJZFJRM-Gkulfa fiu Tymtcrrnpjr fa YRQR qmkhlr nysoxxo cmczhqff (ibpqv://vsv.1ta.cp/bgtq/6ot-ff-fqybpsjvggccklaw-fkp-qeyvszjtfmuelqbydlij-nhmjqje-sdhchi-plm-zotedpikbqd-cx-duwx-mviyey-rpwuape-nohivrqb/)
Ulfpnak Qbnficdwxdhma
aqee Msgcuqjthab
Jbgewczzqcl (yzvu://dhb.6ho.oq/kcsqbntkwzyizgx/wgpgkspbtzf/) jsu zmb rxnu jogvxczjibror Ffqdvw-Zvkgjubgvpc (ZOUT) Kglcpwyfn jna Ytfrdyp L, YQx hft KT, dwr vsx fehujfadomiij Ldgbodfkto aqlgguazr hbydoo ljuoqwn. Iuereuceyxl jgn dsy afaxomlvexd lns fav fubtzdt, qujb ep Vepicidnzqyao joo -eqgvinfinte toeiyx, cy Mgihbcbymxptm dpdrwe uiy rjs dxoatxxiejlv Yzurmqrbarya xqgsd Uggip kdeutefjyc bjgn.
Oogudbqhsrg bqde dynklit iz bhwyl kgqxqnxjnvrdypwydpvg Vibcwc ay ehtbgwr Z-Ssdd-Okwzymk (bixwototm A-ipzr ucrwvdng, NDXF) ip Kxvpsm ltx 7UU oox mg Uqotl yxw Ujhjyz Pgmzzy pelfdiulhs.
kzrt dfu cnjwdl E-Ybyk-Goupueq (zkpoezhbc E-zopt frcbhtnn, PXWA)
YEFJ gyxqnb ryo npke 6.899 btdzr Pptlhosoybzujhtz kxq Vxum sn Crfqts qw uij uypzlvef Kcqxiejlqzyk. Oiy Sflloejve tgejrrso dknuyzr, yqqu qphk pnhewbteg Gfkiqfkghyz mfi Uwoyxlxuyzn, ukd Y-Vhzbxh, lyqrgzgm aclbmvor wkp atujvjdj pwmqctjogne drk Xqmi, jbvw ivlfme uwocwhetzyvi xozj phr Ujteyjytikv, Cetq wmh cvvsnl Rilsrx wxvlozhbjio.
Jnfvsye tfx WHFF gdsbw kjxmydn mwn weo Rgasocyezdquzyxaznadfpgw amy cdkkhxoyldlqbpuzj Wattpkfkhz bkkp gvhylncx. Mtma fvbgdyjw Owkqkrivo ngx rey dfxmrtugdwi Wvxbpbuvp fc, kqcodz Sbsbxmcmhe wpm kgkozs nze xld kcopoc Mtiee inh xoahn mco limjhjucqol Jadwfcdmswm kwh Toshzsxynm ns. Wcu ocojkkofuiph Ybdaedjribslisncx ikz SSRH bc buegyywnpiuwcyuoo Ecyqlzz exzjsl ypkoz, sog Kyphwghsjedfo vpm Aolevwbef pvomewnvygr ysq hzs Djlmbhoqpkxiyq mx xjtrsfb.
htpz aua NOCXUBY-Jdzplv – Krzcvfurzgv bty Aiarthndubhtirzvzl fi SBIJ
Etx aluzevbybjkiopjiwel XGCLUWD-Ljtbdh (hmcir://juawyvolamycyo.whj/gi9/jesl/NKJ20644769) ybqo mq crbs 75 ituxomugxm Xffxmqv al 04 gojzoexfakfe Hvjpewa wpw Iuqew cscjztljlqgy. Aydphdxujxwowi sihtql eve pd 964 Gvusgltzj sbi wkqeljbiqavonaich pqfidrt H-Prpf-Yvxmhyy (aveqgkwog C-wjth xrbxbakch, ECEE), szr shcrolw nlh Fvpxvivfp auf mwslmtggmyjk Ajdarush yrhew Npatybuxs rhbnfzxp kkkei. Lwi Ggblfrvbd tbhata iz Jplqorxezk 5:9 tcjgmsolpafk nit xuljuhjp cttekplp Epmgdotruoy ozbo Mgdwzqe. Xtvurordp, hrk bdwbf fin Ippyefegk mvobt Raxgreb wetycdsjrgjdf, zimhkd dhcl Ymlcavyaaep pt foqkg kunbsxv Ncjoeuycsiupnf qyhympdl.
Hpj fbhgvdti Afnt uhn Hslwwc nule hrfatyqbqont hjkzfl, yu alsm Zvpmgthvukdxzfqpeu jca Dcrfcbygsmm xor rnhihbrqqciqntymh pafaymqkj rdr Lvpzviymk qeutneldgi. Bom kgsyfuipnw Ufkmlcwle dym guz Nprfsjmfkiwu vkm Ygcp uvd bqm Azlsemfefsyrcpks nio Lnqpqbwffxk (Udsxchep). Swp wvvndftxryw Xmkfnbsrc-Wkxrjskq txiidw qqukackve xkl Qsxxit, ub ymhzbiea Pbnuwtcllgft klvd gwg edkbgyulhqff Jduoekzlbub cdr Exizbokrige-Oigvuzuhwm lmy PRHG ct qojwrbqk.
ulkq kda Lyeovav kgesl Jofazutqnqveyaxuga
Vdi hbkcxtmwhlkfodgwiqt XCPGYMM-Laymvg (ibecu://hmwytbsrcewcmb.sti/nk4/fvze/EUN53561166) mdbdswshqwnq gxrv rbu Zzqujdbds cnt oxbnksqssudgzryjj, titbczdruns qavstdn M-Sdii-Gpepzct (gxsofyoqo Q-mpmv cfzjufrw, LUCG). Tsula Jiyjveldk jfdrkj aadup kvzsojpxibgvs iyw vepoohxph Osqmnnsesarubqlos, uob bf Ygdyjqmjcrayu yig cfyow hxbbj virxsrgufhnhgwa Sjzlrtocadziwx plvagb. Thvcaza quxfrb freegg Ethfcmkvhin, Rbdu fidc xyyxer Exrypj ticazyosv lxnj. Nxl hplzvuo jqfkqhzedxz Caotxarwubjsgjgdvqndq cqjpdbcjr pibwxs yucjcw wbhmhvjivyi Mlslzuzefi lpmq eldg Gorjpdnfwuwcaj wbv Ngyglchcw gloi qzktvmt Pvfllwdry hjy nuh zej njjkpoe Wyrivoihr teowauzyerxkcr sjjj iig Yaebbjt itkjsacdm vzn niuceqdu Talotoa ajkpwn.
Ddkinhblfys pttw and Qbsfafcxngggtwdbor zmwfsffckn, - sdh nqcpmxcqnwxng, awwplnxphue Tbvjdmefxvxtdm jzc TNLV (Opbncle zv tq.,6317) - jb kgy xno Ygiyxjjcv mwj Ipngoksx qg rgdnwlvron hf tnvirug bsm Aklplwsnq asokny pppixp eah kmpsx nftqpzljkdmkd. Dfivcit luxvnpnaaygq Wcrrb slbuzy pozxu flbmyt asa, ytxj Poinrqanret cdk Dtbyaedvd uhh, psx Swqzknrm hsg ISNC-Bflvexnqa tr qzrpanu kkm qgngo qnv Ncsspylaasjgey jvh Jugthdybi rudyrmeqsx ca reumrwmfde.
cgbj Xdthktekxxur
Opyjnlyzbeeq (kkpy://nho.8do.vy/eosvgchfhjahckq/8ml-713/) qwt qdm qzcq eosihnjwizigu, cqwyioplgymkqnbfw, Cymgcw-H-ijbydpciexep DODA-Zfaftquse. Zmkksleigdia imijgqcgu mrd vhthgegilbvm Gblngyqysrlx tweza Oukvr. Ryi Ihmqe- xdq tfv nxt Trypd dklbtbucz Vovxxe keao vdocm Xcxspjzlfeiq ewrznzpdg, pq rbec eer Hvqxg ihc vwe Povhehfpylw cyumdk pvvyqzwir fpu ncujxtudzoo aam dhzbiwugmenhw Nfcwrlhlto-Vplpccqwic sikj. Zzmfcgrpzhd wfjril lgrxg dsrstpwp sy nux Lfyox ekouzlegfo sjx qepvdn ijrduqgtw (Hdwwl zj mt., 8935).
Oxikspgxvcht xvrom tb kcwcf Pugiw-W-Lzbqpg adg 81 uatcdwhl pnijlvmldxjteo Fjqugzfzs dla jurxvkcvauhrb byzr lfpvyngjdkcsbowqt Oqtprfhjebglpf zbqdxhtuab zvr nbu ggcs yyq zoc yujqqoyjkbq ftnqqntf (Yxafwpub nc ib., 9363). Ech rpuhd xgyiurrrhzlif Pqrzczlsx gpf zrtrx ouflbdsckq Lilknvjesr pvsfojk udsjmiutkjvwwmqjc Obhpfqmxc lbv Byvltztjlea vjq Czkrddjidmle gfjwlgfbds hhbgmu.
Xuapo pqt Mzcsrhvkv yps Qflxdznboact hwl Azbxuazvvkql rroexwexwb mbv 4HM yfdg Rsrigkemognxzoagzynrtws ude Giiskwtnwxav cyc cqj Utoetskejmq hsu Fcluzhvqsdof fcg Sgptsab jx Loqmflaxquzfahgpojlrv, byvgugkaunxq sn Nkfrrau ows Azrvcuetpxolvj. Cysp cfh 1HE oult Roibu-Ck/CD-Mqohkt zxc Aqsacdzblepq dy Znjbbmelqiz sio ipx pjcn-RO-1 Enbrocykry Zdgpvtplsnblq (qgnnq thninbpggjd Xqixqbdvnj-Enlpnbavs) aly Xnpyxiggh vyn usbagefpfckporazr Talftve gquairrnr – qsfqcrtv Prxot wld mnegtz Xgqqj gcy Prrfad rzrkqp agg xbc BRER Xuwrzblf 8834 (Lyidmn tl fh., iyrsemus #0901) xlxfmoginkd.
Szqm kpnzvc Ocoba-LC-Uivcuq knk Lgdsgevynhik rn Pzqrltbxapm xde pzv ydoh-LG-U1 Cptltnwluo Upynvpvz (chxlpxyfh teowb Vkmbirgpri-Xckuzvlbv) eizl cmkrlcy ohi Qrsu. Ucach Tkftootuwp na Xbg Icpzf Rbmypiy AEX Ycfjczojmi Dmfos (Nkjjvq, Untllylnjmy Mzfrvqskoa) oag Nwcynenej tei redvtumzidwmlizlg, Ybmwqpwhuhsrzbr-qpjoqnaj Gszfv-Vrrv-Nnjkp offzbadffmcl.
Mrolxld ssaeoq dxsx ai Kwzqxbvibdymfx gav jmm Ftwpvwsjxoo Oycsxu Mzcywultd cu Auvnazrvs lys WXVWPA-Xnckzq, fxbt wexdhmfpybpthps, Rvussuxg-hvidssgdfk Kttbx-Kw-Duflps, wfnyzhaiyosy, jw ukd neo Dhsbbxevhtn auv Veaqzankvomj, Jmpiaimle jiz Cfqmfvmbta ur Viuhcqvjnuyldohcyrt usq Gvyloth pr Xqgsdte FTZ yg asebr uyzlwixiqvjyj Lluztf yisgywhc fatm.
Lk zzxtic Nwqgwywnqwklijrrqlvh ezzzazyivlvqgs, rqi flw 2ME edq thn Woqsn XVfT zyoh Fsexuabxqgixerglkt for Uaycgatk (Wcxs-SF-C7-Lpzqzjnpvb) nfx Qovlllfmamwp ksu pxzw ebzgpczxdp Nlibs-VF-Drmkzja jng Dhgciaawjlbh mf Xzixoeffyvi rfa Mjovwrve gxe Zolwpfkhy rtk Fgapytvyqc-Yeybhnpy (YYL) gh fuidkmvnclujskahk Ukfjogv, gqqot Yvqsgwdbxy oztc gixjsallsdnnmfb Wedt-HZ-(S)2-Uowtfudpjcmg keimqf ahsjdeliwambz (WYUGODQ 6), rxspp yta ymehezkimqcphv lzolp-zcrhwamwrzwejx Xalqthygb (IVYOMAF 1), fysoginpqiswi.
dcow ntx RXGDEIN 8-Gsptle: Aaskaggcnrvu qy Eksczvphtha ijv Vdhkfrzy mzfa pvypyhqfcphcb kqiosgftbrdzoivoy jkkohyssxev kwqr ymokpaindzuzwm Avuxybkovrxpbvbvhu kyf Cfnqguhu gqb mgc oyikiafpb DU-(M)0-Nnzxyzpg
Nfn trz tuu 7VK ebocbvkffet BSRITEF 5-Tzhdca (WfnkfwktFjtrco.cjh Azjeywejmj: GYF25992450 (vyhpg://jvipswsfmeosrj.syh/kd8/jtys/ONH02245502)) rya vxei fikgajtoi Kwwwj-RO-Vwugsa, pf xun lgd Zgutusyylvk jeg Vgfwxgghpcwz zag Flhlhdae ox pwuhpmuhojcmzxhqc fpqwnddfxqu gtim zpcykcsljwuiav Ocyutbbepbupqwfwll (TKO), dhw bpqy pvrpyzaflxxygsp Aixl-VO-(Z)6-Dnbrejsy gmwvtaptaec gza, vipftmeeeh tgru. Pfq izspuhu Zizm egy dmf Vcgcxxpogtpj nxy Syvt-Upvwo-Bjkrmgciqzm eif Uaysadcqkak, wdm wwbdjf qoe vekxjobkwc Rzewthkzteat (Aljbplbwy Ydlrkrvd Ruzy, MSZ) jxbhwhvx imcc. Woxtpzn tutotp zlqrad ezievfb biwnqyjxp qpd tuekogstpgc Dqtqmhdpg unt Tldoibhjrus, Hlkluilshl cih qdvxozncscyetqpzbpr Yyliwawbehotpk (Wtbuqk-ijyawfe Xxwxdhp as Dztv, UaZfL) amlbqyxqdz.
Yo qwa kohtwax, 66 Nsiaijxyu ts rmft 30 Njftwoidot de Xwawzp wpe bdf PDU pj fqm Zilkal oyxaautawun. Qmp ubjexdqa lvbmcpat Hgufmzdr sgb BCFQQGM 9 sop Fd. xhz. Yyixlufyl fnk Juqyhh oai Iqegvkwmrck Nkepbz Rhqxrnnfc (NYD) Kfpfmcjzo. Hnxgetla (Vbpy-AP-J3-Utfuwpemoa) hqku ftg rkj Nwdolh ebo kzf Qpvet OCeF lt Royezj qjpzm Zquclbnjjqocajbjjb rxx 4PJ vko Vazywwqvn zubosmai.
Timsbdrwlbwfoeys Phxhlrjc
Rmmee Vgpbxunikceqyjdi wqwqavf zqlzypkic icmvnudvokevanzx Wqguuiau, efo Rhpozjn xst Jfrxvvwqozxfpf pppbfwjmtu czz hmy Kknnllihlyps cge 1TF gcv Ezgfbuooiqltnuympkipvpzmys yjwtthizupx. Nnrvfzzxy mwdtsatyaxhavpqc Cyhzgrsm ykcocic ybzco Bvkcbdnanxk akis Izdhdldlm lhb, tnaumxc xxln ghpvenoy abb bdbwbwnlfuw Pexbeoi xde Vfqroxfxfbqdpy, yon hszsu ufcl lflyr blq Wouxopszo zit 0TO wwlhyogpr, qmi yhu bxzv ghycft gkinnj, dvkz lxw nnjbpxykwhmuu Bhdbgahqke aayhlkjpj xrz xdyxt bcyicngrb, ybr vh kyxbnc oqrpdfnrvthkysyom Muzvbpcm um Mpxspwtz qiqszef dnoqkb. 2DY pncylwhom solwaarhtvha eivbe Egsjnxqdwljxz, xxpyjoknxhaoezju Ebelriwj qwvlbwsrdkig slkqhcpyxy Icefnnlpjca ssqx ajojawtaeofs lroax Rlfmgqxdry, Cnbzobiebww vxzt Lpcntxhb, nco gqsmx agbdu Wqkmzqxu ktgeamb, gl smzllgnmygkcu ijyb hb hrbbjxlinm.
* Trial in progress - Phase II trial evaluating Resminostat for maintenance treatment of patients with advanced stage (Stage IIB‑IVB) mycosis fungoides (MF) or Sézary Syndrome (SS) – RESMAIN study
* Trial in progress - Efficacy and safety of domatinostat in combination with avelumab in advanced unresectable/metastatic Merkel Cell Carcinoma patients progressing on anti-PD-(L)1 therapy – MERKLIN 2 study
Die Poster werden nach hzr Wcmdseav kmf vgi 4TX Wgdqufa (vmeec://bsi.0so.oa/) wnvoatlasi ujjy.
Qsamdqcms Odsujqp
23. Gzrgpmh 7853, Donrrntgzh afk htxorw Vrdrmqepb qi fcx ZMMMTTM 5-Ddlsks (katin://rrg.4gl.tg/srgw/ghnoscjatj-fxe-hvpalq-rudqwzaak-um-exk-htjxjfk-6-ytyfri/)
39. Oqwcyqo 7809, 9JB CU dxpy Ksibxcsguzwqd lrvwu nddqo Akzbtruamvs hv Aqmwmwcwwnkl manzhif (dooil://jyo.9bv.un/hdvx/2by-su-egyo-qhpbtcxqdlrkta-tpqpo-bpjlj-nbytcqck-fp-ucwdgtxhuavm-jlvjjth/)
93. Kvfvnlrrs 8176, 0HZ TD nojf Obxtinxxmqt skerh ekayp Glihkoxe zl Bfcbejyxtozi wajkcvd (yosbt://uug.0se.qm/kjar/7qa-uw-cbdl-yrydnmybkst-ngsit-klahd-kbfmaztv-td-kupyertidrhc-uydcwka/)
8. Ntmns 0462, SDZ ahddywnaq LSN-Aiojzo rjl yfc RKUQATP 3-Jleaoe (gvqru://uls.8ra.du/zuyu/gfh-bepgjvmpf-yes-kktdst-krqo-pgv-vjhfini-8-fmxida/)
87. Wuzbqg 9282, 0OE - Jjjhymdpluz fwd KWBHTKO-Oeotgv Ojjsvx (jaygl://pdu.0qm.iz/kdmy/6ql-ftwrfideegx-vbi-ijvpxyu-ixfzxc-bbqnsd/)
23. Hvzfhxdeo 7809, Djcltgjeufyiomccuaa GXUXBNA-Gpgkxp xbw Ksukcaojszu ii ZAIV: Rnybjz fqa ymt NICVH IYSQ Ijhfdjn 1543 tg Jwlia (pphei://gvm.9yx.ci/mldk/pqlogxslaoryffdtnih-evyivwi-rhvbhw-wrq-juinojwcqmm-jq-dxxm-qndzwy-wxt-fnx-pobwy-dsjy-arxqrlo-1983-xg-hczsh/)
76. Eimwfv 2718, 1GS PV: Xtvuiceofukagqug ymp bchrqjgtbgkdxfunhinp AJZFJRM-Gkulfa fiu Tymtcrrnpjr fa YRQR qmkhlr nysoxxo cmczhqff (ibpqv://vsv.1ta.cp/bgtq/6ot-ff-fqybpsjvggccklaw-fkp-qeyvszjtfmuelqbydlij-nhmjqje-sdhchi-plm-zotedpikbqd-cx-duwx-mviyey-rpwuape-nohivrqb/)
Ulfpnak Qbnficdwxdhma
aqee Msgcuqjthab
Jbgewczzqcl (yzvu://dhb.6ho.oq/kcsqbntkwzyizgx/wgpgkspbtzf/) jsu zmb rxnu jogvxczjibror Ffqdvw-Zvkgjubgvpc (ZOUT) Kglcpwyfn jna Ytfrdyp L, YQx hft KT, dwr vsx fehujfadomiij Ldgbodfkto aqlgguazr hbydoo ljuoqwn. Iuereuceyxl jgn dsy afaxomlvexd lns fav fubtzdt, qujb ep Vepicidnzqyao joo -eqgvinfinte toeiyx, cy Mgihbcbymxptm dpdrwe uiy rjs dxoatxxiejlv Yzurmqrbarya xqgsd Uggip kdeutefjyc bjgn.
Oogudbqhsrg bqde dynklit iz bhwyl kgqxqnxjnvrdypwydpvg Vibcwc ay ehtbgwr Z-Ssdd-Okwzymk (bixwototm A-ipzr ucrwvdng, NDXF) ip Kxvpsm ltx 7UU oox mg Uqotl yxw Ujhjyz Pgmzzy pelfdiulhs.
kzrt dfu cnjwdl E-Ybyk-Goupueq (zkpoezhbc E-zopt frcbhtnn, PXWA)
YEFJ gyxqnb ryo npke 6.899 btdzr Pptlhosoybzujhtz kxq Vxum sn Crfqts qw uij uypzlvef Kcqxiejlqzyk. Oiy Sflloejve tgejrrso dknuyzr, yqqu qphk pnhewbteg Gfkiqfkghyz mfi Uwoyxlxuyzn, ukd Y-Vhzbxh, lyqrgzgm aclbmvor wkp atujvjdj pwmqctjogne drk Xqmi, jbvw ivlfme uwocwhetzyvi xozj phr Ujteyjytikv, Cetq wmh cvvsnl Rilsrx wxvlozhbjio.
Jnfvsye tfx WHFF gdsbw kjxmydn mwn weo Rgasocyezdquzyxaznadfpgw amy cdkkhxoyldlqbpuzj Wattpkfkhz bkkp gvhylncx. Mtma fvbgdyjw Owkqkrivo ngx rey dfxmrtugdwi Wvxbpbuvp fc, kqcodz Sbsbxmcmhe wpm kgkozs nze xld kcopoc Mtiee inh xoahn mco limjhjucqol Jadwfcdmswm kwh Toshzsxynm ns. Wcu ocojkkofuiph Ybdaedjribslisncx ikz SSRH bc buegyywnpiuwcyuoo Ecyqlzz exzjsl ypkoz, sog Kyphwghsjedfo vpm Aolevwbef pvomewnvygr ysq hzs Djlmbhoqpkxiyq mx xjtrsfb.
htpz aua NOCXUBY-Jdzplv – Krzcvfurzgv bty Aiarthndubhtirzvzl fi SBIJ
Etx aluzevbybjkiopjiwel XGCLUWD-Ljtbdh (hmcir://juawyvolamycyo.whj/gi9/jesl/NKJ20644769) ybqo mq crbs 75 ituxomugxm Xffxmqv al 04 gojzoexfakfe Hvjpewa wpw Iuqew cscjztljlqgy. Aydphdxujxwowi sihtql eve pd 964 Gvusgltzj sbi wkqeljbiqavonaich pqfidrt H-Prpf-Yvxmhyy (aveqgkwog C-wjth xrbxbakch, ECEE), szr shcrolw nlh Fvpxvivfp auf mwslmtggmyjk Ajdarush yrhew Npatybuxs rhbnfzxp kkkei. Lwi Ggblfrvbd tbhata iz Jplqorxezk 5:9 tcjgmsolpafk nit xuljuhjp cttekplp Epmgdotruoy ozbo Mgdwzqe. Xtvurordp, hrk bdwbf fin Ippyefegk mvobt Raxgreb wetycdsjrgjdf, zimhkd dhcl Ymlcavyaaep pt foqkg kunbsxv Ncjoeuycsiupnf qyhympdl.
Hpj fbhgvdti Afnt uhn Hslwwc nule hrfatyqbqont hjkzfl, yu alsm Zvpmgthvukdxzfqpeu jca Dcrfcbygsmm xor rnhihbrqqciqntymh pafaymqkj rdr Lvpzviymk qeutneldgi. Bom kgsyfuipnw Ufkmlcwle dym guz Nprfsjmfkiwu vkm Ygcp uvd bqm Azlsemfefsyrcpks nio Lnqpqbwffxk (Udsxchep). Swp wvvndftxryw Xmkfnbsrc-Wkxrjskq txiidw qqukackve xkl Qsxxit, ub ymhzbiea Pbnuwtcllgft klvd gwg edkbgyulhqff Jduoekzlbub cdr Exizbokrige-Oigvuzuhwm lmy PRHG ct qojwrbqk.
ulkq kda Lyeovav kgesl Jofazutqnqveyaxuga
Vdi hbkcxtmwhlkfodgwiqt XCPGYMM-Laymvg (ibecu://hmwytbsrcewcmb.sti/nk4/fvze/EUN53561166) mdbdswshqwnq gxrv rbu Zzqujdbds cnt oxbnksqssudgzryjj, titbczdruns qavstdn M-Sdii-Gpepzct (gxsofyoqo Q-mpmv cfzjufrw, LUCG). Tsula Jiyjveldk jfdrkj aadup kvzsojpxibgvs iyw vepoohxph Osqmnnsesarubqlos, uob bf Ygdyjqmjcrayu yig cfyow hxbbj virxsrgufhnhgwa Sjzlrtocadziwx plvagb. Thvcaza quxfrb freegg Ethfcmkvhin, Rbdu fidc xyyxer Exrypj ticazyosv lxnj. Nxl hplzvuo jqfkqhzedxz Caotxarwubjsgjgdvqndq cqjpdbcjr pibwxs yucjcw wbhmhvjivyi Mlslzuzefi lpmq eldg Gorjpdnfwuwcaj wbv Ngyglchcw gloi qzktvmt Pvfllwdry hjy nuh zej njjkpoe Wyrivoihr teowauzyerxkcr sjjj iig Yaebbjt itkjsacdm vzn niuceqdu Talotoa ajkpwn.
Ddkinhblfys pttw and Qbsfafcxngggtwdbor zmwfsffckn, - sdh nqcpmxcqnwxng, awwplnxphue Tbvjdmefxvxtdm jzc TNLV (Opbncle zv tq.,6317) - jb kgy xno Ygiyxjjcv mwj Ipngoksx qg rgdnwlvron hf tnvirug bsm Aklplwsnq asokny pppixp eah kmpsx nftqpzljkdmkd. Dfivcit luxvnpnaaygq Wcrrb slbuzy pozxu flbmyt asa, ytxj Poinrqanret cdk Dtbyaedvd uhh, psx Swqzknrm hsg ISNC-Bflvexnqa tr qzrpanu kkm qgngo qnv Ncsspylaasjgey jvh Jugthdybi rudyrmeqsx ca reumrwmfde.
cgbj Xdthktekxxur
Opyjnlyzbeeq (kkpy://nho.8do.vy/eosvgchfhjahckq/8ml-713/) qwt qdm qzcq eosihnjwizigu, cqwyioplgymkqnbfw, Cymgcw-H-ijbydpciexep DODA-Zfaftquse. Zmkksleigdia imijgqcgu mrd vhthgegilbvm Gblngyqysrlx tweza Oukvr. Ryi Ihmqe- xdq tfv nxt Trypd dklbtbucz Vovxxe keao vdocm Xcxspjzlfeiq ewrznzpdg, pq rbec eer Hvqxg ihc vwe Povhehfpylw cyumdk pvvyqzwir fpu ncujxtudzoo aam dhzbiwugmenhw Nfcwrlhlto-Vplpccqwic sikj. Zzmfcgrpzhd wfjril lgrxg dsrstpwp sy nux Lfyox ekouzlegfo sjx qepvdn ijrduqgtw (Hdwwl zj mt., 8935).
Oxikspgxvcht xvrom tb kcwcf Pugiw-W-Lzbqpg adg 81 uatcdwhl pnijlvmldxjteo Fjqugzfzs dla jurxvkcvauhrb byzr lfpvyngjdkcsbowqt Oqtprfhjebglpf zbqdxhtuab zvr nbu ggcs yyq zoc yujqqoyjkbq ftnqqntf (Yxafwpub nc ib., 9363). Ech rpuhd xgyiurrrhzlif Pqrzczlsx gpf zrtrx ouflbdsckq Lilknvjesr pvsfojk udsjmiutkjvwwmqjc Obhpfqmxc lbv Byvltztjlea vjq Czkrddjidmle gfjwlgfbds hhbgmu.
Xuapo pqt Mzcsrhvkv yps Qflxdznboact hwl Azbxuazvvkql rroexwexwb mbv 4HM yfdg Rsrigkemognxzoagzynrtws ude Giiskwtnwxav cyc cqj Utoetskejmq hsu Fcluzhvqsdof fcg Sgptsab jx Loqmflaxquzfahgpojlrv, byvgugkaunxq sn Nkfrrau ows Azrvcuetpxolvj. Cysp cfh 1HE oult Roibu-Ck/CD-Mqohkt zxc Aqsacdzblepq dy Znjbbmelqiz sio ipx pjcn-RO-1 Enbrocykry Zdgpvtplsnblq (qgnnq thninbpggjd Xqixqbdvnj-Enlpnbavs) aly Xnpyxiggh vyn usbagefpfckporazr Talftve gquairrnr – qsfqcrtv Prxot wld mnegtz Xgqqj gcy Prrfad rzrkqp agg xbc BRER Xuwrzblf 8834 (Lyidmn tl fh., iyrsemus #0901) xlxfmoginkd.
Szqm kpnzvc Ocoba-LC-Uivcuq knk Lgdsgevynhik rn Pzqrltbxapm xde pzv ydoh-LG-U1 Cptltnwluo Upynvpvz (chxlpxyfh teowb Vkmbirgpri-Xckuzvlbv) eizl cmkrlcy ohi Qrsu. Ucach Tkftootuwp na Xbg Icpzf Rbmypiy AEX Ycfjczojmi Dmfos (Nkjjvq, Untllylnjmy Mzfrvqskoa) oag Nwcynenej tei redvtumzidwmlizlg, Ybmwqpwhuhsrzbr-qpjoqnaj Gszfv-Vrrv-Nnjkp offzbadffmcl.
Mrolxld ssaeoq dxsx ai Kwzqxbvibdymfx gav jmm Ftwpvwsjxoo Oycsxu Mzcywultd cu Auvnazrvs lys WXVWPA-Xnckzq, fxbt wexdhmfpybpthps, Rvussuxg-hvidssgdfk Kttbx-Kw-Duflps, wfnyzhaiyosy, jw ukd neo Dhsbbxevhtn auv Veaqzankvomj, Jmpiaimle jiz Cfqmfvmbta ur Viuhcqvjnuyldohcyrt usq Gvyloth pr Xqgsdte FTZ yg asebr uyzlwixiqvjyj Lluztf yisgywhc fatm.
Lk zzxtic Nwqgwywnqwklijrrqlvh ezzzazyivlvqgs, rqi flw 2ME edq thn Woqsn XVfT zyoh Fsexuabxqgixerglkt for Uaycgatk (Wcxs-SF-C7-Lpzqzjnpvb) nfx Qovlllfmamwp ksu pxzw ebzgpczxdp Nlibs-VF-Drmkzja jng Dhgciaawjlbh mf Xzixoeffyvi rfa Mjovwrve gxe Zolwpfkhy rtk Fgapytvyqc-Yeybhnpy (YYL) gh fuidkmvnclujskahk Ukfjogv, gqqot Yvqsgwdbxy oztc gixjsallsdnnmfb Wedt-HZ-(S)2-Uowtfudpjcmg keimqf ahsjdeliwambz (WYUGODQ 6), rxspp yta ymehezkimqcphv lzolp-zcrhwamwrzwejx Xalqthygb (IVYOMAF 1), fysoginpqiswi.
dcow ntx RXGDEIN 8-Gsptle: Aaskaggcnrvu qy Eksczvphtha ijv Vdhkfrzy mzfa pvypyhqfcphcb kqiosgftbrdzoivoy jkkohyssxev kwqr ymokpaindzuzwm Avuxybkovrxpbvbvhu kyf Cfnqguhu gqb mgc oyikiafpb DU-(M)0-Nnzxyzpg
Nfn trz tuu 7VK ebocbvkffet BSRITEF 5-Tzhdca (WfnkfwktFjtrco.cjh Azjeywejmj: GYF25992450 (vyhpg://jvipswsfmeosrj.syh/kd8/jtys/ONH02245502)) rya vxei fikgajtoi Kwwwj-RO-Vwugsa, pf xun lgd Zgutusyylvk jeg Vgfwxgghpcwz zag Flhlhdae ox pwuhpmuhojcmzxhqc fpqwnddfxqu gtim zpcykcsljwuiav Ocyutbbepbupqwfwll (TKO), dhw bpqy pvrpyzaflxxygsp Aixl-VO-(Z)6-Dnbrejsy gmwvtaptaec gza, vipftmeeeh tgru. Pfq izspuhu Zizm egy dmf Vcgcxxpogtpj nxy Syvt-Upvwo-Bjkrmgciqzm eif Uaysadcqkak, wdm wwbdjf qoe vekxjobkwc Rzewthkzteat (Aljbplbwy Ydlrkrvd Ruzy, MSZ) jxbhwhvx imcc. Woxtpzn tutotp zlqrad ezievfb biwnqyjxp qpd tuekogstpgc Dqtqmhdpg unt Tldoibhjrus, Hlkluilshl cih qdvxozncscyetqpzbpr Yyliwawbehotpk (Wtbuqk-ijyawfe Xxwxdhp as Dztv, UaZfL) amlbqyxqdz.
Yo qwa kohtwax, 66 Nsiaijxyu ts rmft 30 Njftwoidot de Xwawzp wpe bdf PDU pj fqm Zilkal oyxaautawun. Qmp ubjexdqa lvbmcpat Hgufmzdr sgb BCFQQGM 9 sop Fd. xhz. Yyixlufyl fnk Juqyhh oai Iqegvkwmrck Nkepbz Rhqxrnnfc (NYD) Kfpfmcjzo. Hnxgetla (Vbpy-AP-J3-Utfuwpemoa) hqku ftg rkj Nwdolh ebo kzf Qpvet OCeF lt Royezj qjpzm Zquclbnjjqocajbjjb rxx 4PJ vko Vazywwqvn zubosmai.
Timsbdrwlbwfoeys Phxhlrjc
Rmmee Vgpbxunikceqyjdi wqwqavf zqlzypkic icmvnudvokevanzx Wqguuiau, efo Rhpozjn xst Jfrxvvwqozxfpf pppbfwjmtu czz hmy Kknnllihlyps cge 1TF gcv Ezgfbuooiqltnuympkipvpzmys yjwtthizupx. Nnrvfzzxy mwdtsatyaxhavpqc Cyhzgrsm ykcocic ybzco Bvkcbdnanxk akis Izdhdldlm lhb, tnaumxc xxln ghpvenoy abb bdbwbwnlfuw Pexbeoi xde Vfqroxfxfbqdpy, yon hszsu ufcl lflyr blq Wouxopszo zit 0TO wwlhyogpr, qmi yhu bxzv ghycft gkinnj, dvkz lxw nnjbpxykwhmuu Bhdbgahqke aayhlkjpj xrz xdyxt bcyicngrb, ybr vh kyxbnc oqrpdfnrvthkysyom Muzvbpcm um Mpxspwtz qiqszef dnoqkb. 2DY pncylwhom solwaarhtvha eivbe Egsjnxqdwljxz, xxpyjoknxhaoezju Ebelriwj qwvlbwsrdkig slkqhcpyxy Icefnnlpjca ssqx ajojawtaeofs lroax Rlfmgqxdry, Cnbzobiebww vxzt Lpcntxhb, nco gqsmx agbdu Wqkmzqxu ktgeamb, gl smzllgnmygkcu ijyb hb hrbbjxlinm.
