The VITROCELL® 12/12 module system has been designed to facilitate the exposure of mammalian cell cultures to airborne substances such as gases, complex mixtures, nanoparticles and fibers. It features a throughput of 3 dilution steps @ 3 replicates and 1 clean air control at 3 replicates. In order to optimize the exposure for liquid aerosols and to maximize the performance of humidified air supply it is now also available in a user-friendly climatic chamber.
Exposure at the Air/Liquid Interface
In response to the scientific need to expose in physiologically relevant conditions, the VITROCELL® exposure devices have been specifically designed to enable direct exposure of mammalian cells or tissue at the Air/Liquid Interface. Here the cell cultures are not covered with media as opposed to submerged conditions which cause an undesired interaction of the formerly airborne substances with the culture media. Cell systems cultivated on membrane inserts are exposed at the Air/Liquid Interface (ALI) so that the test substances are received directly. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® 12/12 Climatic Chamber with Docking Station
The VITROCELL 12/12 System and it’s docking station are integrated in a Climatic Chamber which is heated at 37° C. The heating of the entire system avoids condensation of aerosols provided by a liquid aerosol generator or by e-cigarettes /electronic nicotine delivery systems (ENDS). Furthermore, the constant temperature enables a perfect supply of humidified air (normally 85 % R. H.)
Key Features:
Exposure at the Air/Liquid Interface
In response to the scientific need to expose in physiologically relevant conditions, the VITROCELL® exposure devices have been specifically designed to enable direct exposure of mammalian cells or tissue at the Air/Liquid Interface. Here the cell cultures are not covered with media as opposed to submerged conditions which cause an undesired interaction of the formerly airborne substances with the culture media. Cell systems cultivated on membrane inserts are exposed at the Air/Liquid Interface (ALI) so that the test substances are received directly. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® 12/12 Climatic Chamber with Docking Station
The VITROCELL 12/12 System and it’s docking station are integrated in a Climatic Chamber which is heated at 37° C. The heating of the entire system avoids condensation of aerosols provided by a liquid aerosol generator or by e-cigarettes /electronic nicotine delivery systems (ENDS). Furthermore, the constant temperature enables a perfect supply of humidified air (normally 85 % R. H.)
Key Features:
- Dimensions (L x W x H): 1 280 x 900 x 870 (open 1 350) mm
- Supplied with dynamic double-jet dilution system for 3 dilutions @ 3 replicates and 1 clean air control @ 3 replicates
- Integrated Humidification Station
- Integrated aerosol distribution system made of stainless steel/VITROGLIDE surface
- Climatic Chamber with temperature monitoring
- Unique quick-connect system for easier handling
