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Application note for sample preparation for immunosuppressant using the MassSTAR

(PresseBox) (Martinsried, ) GRAEFELFING, Germany, and BONADUZ, Switzerland, July 2014

Hamilton Robotics together with its partner Chromsystems released an app note about immunosuppressant monitoring using the MassSTAR with Chromsystems’ CE-IVD Mass-Tox® Immunosuppressants kit and corresponding CE-IVD protocol.

The application note shows that completely automated sample preparation for therapeutic drug monitoring of immunosuppressants such as Cyclosporine A, Tacrolimus, Sirolimus and Everolimus from whole blood is comparable with manual processing. Recovery rates are close to 100% and linearity is guaranteed in the therapeutic range. In addition, inter- and intra-day reproducibility is significantly <10%. This shows that the system is perfectly suited for automated sample preparation for immunosuppressants.

For further information on the MassSTAR automated sample preparation system, please visit
For further information on Chromsystems, please visit

About Chromsystems
Chromsystems is a leading global company providing ready-to-use reagent kits and supplies for routine clinical diagnostics by HPLC and LC-MS/MS, the latter representing the gold standard for a large number of parameters. Chromsystem’s product portfolio includes complete kits as well as quality controls and calibrators and enable any laboratory to introduce HPLC and LC-MS/MS methods into their diagnostic routine without prior technical expertise.

About Hamilton Robotics
Hamilton Robotics designs and manufactures fully automated robotic systems for sample preparation and storage. The products range from unique, custom laboratory automation solutions (turnkey solutions) on standard applications validated through partnership programs with renowned life science and diagnostic companies as well as OEM solutions to the top ten diagnostic companies.