Free Download available: offers in-depth Coverage of SARS-CoV-2 Biology

Handbook about the biology of SARS-CoV-2 provides 49 pages of key resources assembled to advance science against the pandemic

Free Download available: offers in-depth Coverage of SARS-CoV-2 Biology
(PresseBox) ( Aachen, )
18 months ago, the SARS-CoV-2 virus first made news and since then has changed the world drastically. The global community continues to see variants of SARS-CoV-2 rise, hence progressing scientific knowledge on the biology of the virus is a must. By May 2021 has supported over 500 COVID-19 R&D projects in diagnostics, drug discovery, and basic research across more than 25 countries resulting in a SARS-CoV-2 handbook. The handbook has 49 pages of key resources and is now available to download for free and with no registration required.

Key resources for COVID-19 research

To overcome the ongoing COVID-19 pandemic, it is essential to understand the underlying biology of SARS-CoV-2 as well as the human body’s response to the virus. Therefore,’s SARS-CoV-2 handbook offers a compilation of key COVID-19 resources.

Part 1 of the handbook addresses the basic biology of the SARS-CoV-2 function as well as the involved virus and host proteins. Part 2 examines the factors contributing to the development of COVID-19. Lastly, part 3 provides background information regarding antibodies and immunoassays necessary for the study and diagnostics of SARS-CoV-2 and COVID-19. Additionally, the 49 pages of up-to-date knowledge includes references to antibodies and proteins used by the scientific community to drive their respective COVID-19 work. 

Understanding the virus

The handbook starts off by laying a sound foundation of knowledge on the SARS-CoV-2 lifecycle, its structural and non-structural proteins and known mutations, as well as the SARS-CoV-2 protein interactome (i.e., the known interplay between 26 SARS-CoV-2 proteins and their human interaction partners).

With this information the reader can further explore the available knowledge on the immune response of the human body which involves several known biological pathways, such as the TLR Signaling or the JAK-STAT Signaling Pathway and the Complement System.

That knowledge helps to grasp how several SARS-CoV-2 proteins manipulate the immune system's response in favor of the virus and how an initial positive immune response may turn into a devastating COVID-19 Cytokine Storm. Applying the acquired knowledge, the reader then gets exposed to key questions in current COVID-19 diagnostics and assay development. 

A must-read for Biomedical Scientists

Since the outbreak of the COVID-19 pandemic, has been a premier and trusted resource for SARS-CoV-2 research. The new handbook adds to this. It has been assembled by the’s scientific staff to advance the efforts against the pandemic and therefore is provided free of charge and without barriers for access. 

“We consider this a must-read for Biomedical Scientists either already involved in SARS-CoV-2 research or just getting started with it. It is also a valuable source of information for the scientifically interested public,” Dr. Andreas Kessell, Co-Founder of sums up. 

Table of contents and barrier-free, free-of-charge download are available here:
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