NOXXON Pharma stellte auf der 55. Jahrestagung der American Society of Hematology (ASH) in New Orleans vom 7.-10. Dezember 2013 vorläufige Daten aus zwei unabhängigen klinischen Phase IIa-Studien des anti-CXCL12/SDF-1 Spiegelmers Olaptesed Pegol (NOX-A12) vor.
In der ersten Studie wurde Olaptesed Patienten mit rezidivierender chronischer lymphatischer Leukämie (CLL) in Kombination mit Bendamustin und Rituximab verabreicht. In der zweiten Studie wurde Olaptesed mit Bortezomib und Dexamethason bei Patienten mit rezidiviertem multiplem Myelom (MM) kombiniert. Die Daten der Pilotgruppen (9 Patienten) aus jeder Studie werden präsentiert.
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In der ersten Studie wurde Olaptesed Patienten mit rezidivierender chronischer lymphatischer Leukämie (CLL) in Kombination mit Bendamustin und Rituximab verabreicht. In der zweiten Studie wurde Olaptesed mit Bortezomib und Dexamethason bei Patienten mit rezidiviertem multiplem Myelom (MM) kombiniert. Die Daten der Pilotgruppen (9 Patienten) aus jeder Studie werden präsentiert.
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