MorphoSys AG (FSE:MOR; NASDAQ:MOR) und Incyte (NASDAQ:INCY) gaben heute bekannt, dass der erste Patient in der zulassungsrelevanten Phase 3-frontMIND-Studie dosiert wurde. Die Studie untersucht Tafasitamab plus Lenalidomid in Kombination mit Rituximab, Cyclophosphamid, Doxorubicin, Vincristin und Prednison (R-CHOP) im Vergleich zu R-CHOP als Erstlinienbehandlung für Patienten in mittleren und Hochrisikogruppen mit unbehandeltem diffusem großzelligem B-Zell-Lymphom (DLBCL). Tafasitamab ist ein humanisierter, monoklonaler Antikörper, der sich effektiv gegen das B-Zell-spezifische Antigen CD19 richtet und eine Aktivierung der Immunzellen bewirkt.
"Während mehr als die Hälfte der DLBCL-Patienten mit einer aggressiven Chemotherapie geheilt werden kann, sind die derzeitigen Behandlungsmöglichkeiten für Hochrisikopatienten unzureichend", sagte Dr. Mike
"Während mehr als die Hälfte der DLBCL-Patienten mit einer aggressiven Chemotherapie geheilt werden kann, sind die derzeitigen Behandlungsmöglichkeiten für Hochrisikopatienten unzureichend", sagte Dr. Mike
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