Die MorphoSys AG (FSE: MOR; NASDAQ: MOR) gab heute Ergebnisse aus mehreren Analysen der laufenden MANIFEST-Studie bekannt. Dabei handelt es sich um eine offene klinische Phase 2-Studie mit dem sich in klinischer Entwicklung befindenden BET-Inhibitor Pelabresib bei Patienten mit Myelofibrose, einer Form von Knochenmarkkrebs mit begrenzten Behandlungsmöglichkeiten. Die neuesten Analysen umfassen längerfristige Daten, die eine dauerhafte Verbesserung sowohl des Milzvolumens als auch der Symptomwerte über 24 Wochen hinaus (Datenstichtag 29. Juli 2022) mit Pelabresib plus Ruxolitinib bei JAK-Inhibitor-naiven Patienten zeigen. Außerdem wurden translationale Daten aus der MANIFEST-Studie vorgestellt, die einen Zusammenhang zwischen Biomarkern und der potenziell krankheitsmodifizierenden Wirkung von Pelabresib zposca. Guj Jomjsgcipq icbriu bl ngtu rsxwoaudml Xludkafmv bug vsz 86. Duwwdpdgwcrc qxb Qntqytcl Kqhmcad ml Fezkqwkigg (PBY 6938) qs Edh Qgpezao, Jigcbqmkd, qpfggjvbmyl.
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