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Micronit develops microreactor module for use in industrial production

(PresseBox) (Enschede (The Netherlands), ) Micronit Microfluidics has developed a microreactor module that enables fine chemical companies to perform fluid reactions on an industrial scale in a continuous process. The module is currently been evaluated by DSM Pharmaceutical Products.

The microreactor is a monolithic glass module of 10 stacked reaction channels with a joint internal volume of 100 millilitres. In the module, a wide range of functionalities have been integrated that enable chemists to mix fluids, let them react, and stop a reaction after a certain time. The temperature of the reaction is actively cooled by means of integrated cooling channels.

Microreactor technology turns fluid reactions that have always been performed in small batches into continuous processes. The switch from batch to continuous flow results in safer and more efficient chemical production. Furthermore, the continuous flow reactors can easily be scaled to obtain extra production capacity for a particular reaction.

"Microreactor technology has been identified by DSM Pharmaceutical Products as a promising way of process intensification, significantly improving the sustainability of some production processes", explains Raf Reintjens, Competence manager Process Intensification with DSM Pharmaceutical Products. "The road to industrial applications requires a close collaboration with suppliers, as the scale up (parallelization) turns out to be not simple. DSM Pharmaceutical Products sees Micronit as one of the suppliers that are capable of this."

Micronit Microfluidics has developed and manufactured microreactors for many years on chip scale. These lab-on-a-chips are particularly applied in synthesis and optimalization research. This development together with DSM Pharmaceutical Products shows that Micronit's technology enables the production of industrial scale reactor volumes.

"We see a growing interest for glass microreactors in the chemical industry," says Ronny van 't Oever, Chief Technology Officer of Micronit Microfluidics. "Microreactors can be designed according to the demands of the chemistry instead of the (batch) reactor dictating how the chemistry should look. This results in a reduction of problems during production scale up, saving time and money. By integrating 10 reactors in one module, less peripheral equipment and lab space is needed, tremendously reducing the total investment. Our know-how and capabilities enable us to supply a reactor solution within a short time."

Micronit GmbH

Micronit Microfluidics develops and manufactures lab-on-a-chip products in glass for the worldwide life science and chemical industry. Micronit has the expertise in microfluidics and in-house production facilities to develop and produce these lab-on-a-chips. Micronit was founded in 1999 from the University of Twente and has 30 employees at the moment. www.micronit.com

For the further development and implementation of the new generation of microreactor systems in the fine-chemical and pharmaceutical industry, Micronit Microfluidics, FutureChemistry and Flowid started a cooperation named Access2Flow a few months ago. www.access2flow.com