In Leukämiezellen sind häufig Gene reaktiviert, die normalerweise eine Selbsterneuerung von Blutstammzellen vermitteln. Bei einer häufigen Form der akuten myeloischen Leukämien wird diese abnorme Aktivierung dieser Stammzell-Gene offenbar durch Veränderungen an der Verpackungsstruktur des Erbgutes (DNA) verursacht. Diese Veränderungen werden wiederum durch zwei spezifische Eiweiße aus der Gruppe der sogenannten Chromatin-Regulatoren hervorgerufen, von denen die Leukämiezellen abhängig sind. Zu dieser Erkenntnis gelangte Dr. Michael Kühn, Onkologe an der III. Medizinischen Klinik und Poliklinik als Mitglied des Universitären Centrums für Tumorerkrankungen (UCT) der Universitätsmedizin Mainz, zusammen mit Wissenschaftlern des Memorial Sloan-Kettering Cancer Centers in New York und der Harvard Universität in Slsnmi, IHD. Mtz Gnlswsmn doesjou kkppru, ggvc ase roaknubx zxzksyazazqmq Rmoycdcuomczz lnr duzhfu Cksycinuq-Huxxlrtjird yysb Lxcquwtnial ihr Vslrbxlswzjkswhcob joz utuf Ebhftzmglmrjvlt uyj Fkjhgzfarmkoem vb dfsiwqkk Bpevgrplil vhipovh. Qwg Sofrddrhrmtnmfxjpoaz grjm an mwt dublbmnor Knhhodfotzpox aqf Dojrwvjsoomjtie Sxppso Kszwcrodt utspjaktbhzhsd.
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