Pressemitteilung BoxID: 759065 (B.R.A.I.N. AG)
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High-tech process optimisation in biogas plants

Biotechnological improvement of a future technology

(PresseBox) (Zwingenberg, Germany, ) Biotechnology specialist BRAIN AG announces achievement of an optimised biogas production process feeding on industrial waste streams. In the programme ESE-BIOGAS, which is funded in part by the Federal Ministry of Education and Research (BMBF), scientists from BRAIN successfully improved the microbial biogas production process, resulting in a 20% higher energy yield compared to known standard processes. BRAIN introduced an additional upstream step in the production of biogas called 'exo-enzyme farm' and already validated the improved process in a 10 litre prototype biogas fermenter-system. This optimised system is now ready-to-use for industrial purposes.

At present, Germany has to import expensive and mostly fossilbased energy sources in order to supply industry and private households with sufficient energy. Economic dependencies and political uncertainties are the inevitable consequences. In order to become more independent from these energy imports in the near future, industrial energy production has to diversify, taking new directions, such as the establishment of sustainable bio-based processes to supplement existing power generation.

In ESE-BIOGAS the research partners together with BRAIN are introducing bio-based energy production processes through the consistent use of renewable raw materials. This covers one of the priority fields of current German research and development programs. ESE-BIO-GAS (reference number FKZ: 03SF0424D) is therefore part of the National Research Strategy Bioeconomy 2030.

In Germany, biogas as energy source accounts for more than 50% of the electrical power produced from biomass and other industrial waste streams. With the clear goal not to compete with carbon sources needed for food and feedstuff production, BRAINs focus is to optimise the use of substrates such as straw, scrap wood and liquid manure, which by using microbial consortia are converted to biogas.

The biochemical conversion of biomass into biogas is a highly complex process in which a diverse microbial consortium is needed.

The complexity of this community in a reactor so far largely precludes reliable control of the fermentation process, which until today restricted the use of this technology in a validated industrial setting. Apart from this deficit in process control the initial breakdown of polymeric biomass into fermentable monomers is fairly slow, which currently determines the speed of the entire process and thus constitutes a further limitation. Another well-known problem in the operation of biogas plants is acidification of the fermentation resulting in heavy disturbance of the process through inhibition of susceptible methane producing bacteria. The consequential failure in degradation/ bioconversion is inevitably connected to economic losses.

The new process established by BRAIN addresses these problems, leading to an increase in stability, sustainability and efficiency of the entire fermentation process. The output-raising improvement comprises three interacting modules for optimal effect: an exoenzyme farm, an electro-biogas fermenter and a biosensor.

"The newly established exo-enzyme farm provides a defined enzyme cocktail that increases the efficiency of the waste substrate breakdown and subsequent metabolic degradation by 20%. Advantages of this process step are an improved space-time yield and a reduced final waste volume. At the core of the reactor is a new electro-biogas fermenter. Herein, the degradation steps of the substrate can be controlled individually by directly implemented fuel cells. In parallel, the energy equivalents (electrons) that are released during the enzymatic reactions are used directly for additional power generation. In comparison to existing combined heat and power plants this works far more efficiently", explains Dipl. Ing. Marc Gauert, project leader at BRAIN. "The last process component is a microfluidic biosensor which monitors the process intermediate propanoic acid, enabling easier process control".

"Within a very short time span, Marc Gauert and his BRAIN team succeeded in effectively optimising of the process of biogas production. Special thanks also go to Prof. Dr. Johannes Gescher from KIT in Karlsruhe, whose excellent experience in microbial fuel cells as well as in exo-electrogenic and methanogenic microorganisms contributed essentially to the positive outcome", adds Dr. Guido Meurer, Unit Head Strain Development at BRAIN.

At the end of 2014, 7,820 biogas plants were in operation in Germany. They had an installed capacity of around 3,500 MW. Compared to the year 2000 the number of plants increased sevenfold. German biogas plants thus replace more than two nuclear power plants and provide more than 10 million households with 27 billion kilowatt-hours of electricity per year (4.3% of the gross power generation). In Germany alone, the biogas sector employed around 40,000 people in 2013 who achieved total sales of EUR 6.6 billion. International business accounted for about 40% of the sales.




BRAIN AG is an industrial "white" biotech company which discovers and develops novel bioactive natural compounds and proprietary enzymes for its partners and customers in the chemical and pharmaceutical industries, as well as the food and cosmetics industries. With its unique approach to the discovery and production of new biological compounds and biocatalysts, the company achieves creative solutions by harnessing nature's untapped biodiversity. Its success is built on its proprietary BioArchive comprising millions of genes, proteins and metabolic pathways from microbial isolates and metagenome libraries. Since its foundation in 1993, BRAIN has entered into over 100 strategic collaborations with nearly all the relevant companies within the chemical industry as e.g. BASF, Ciba, Clariant, Evonik, DSM, Genencor, Henkel, Nutrinova, RWE, Sandoz, Schering, Südzucker and Symrise, to name but a few. Currently, BRAIN employs 120 highly skilled personnel.

The industrialisation strategy, which was successfully launched in 2010 as the company's second pillar of operation next to the co-operation business, has been expanded successfully. It permits BRAIN AG to access the BRAIN Group's entire value chain of different lucrative markets, from the identification of biological solutions and their development to their implementation in the target industries. Currently, the BRAIN Group consists of six companies, all of which operate successfully in the market.


The abbreviation of the ESE Biogas project that is partially financed by the German Federal Ministry of Education and Research (BMBF) in the Bioenergy - Process-oriented research and innovation (BioProFi) programme, stands for electrogenesis, sensor technology and an exoenzyme-based increase in stability and efficiency in biogas production.

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