Die Bayer Schering Pharma AG und das kalifornische Unternehmen OncoMed Pharmaceuticals, Inc. wollen gemeinsam an der Erforschung, Entwicklung und Vermarktung neuartiger Therapeutika gegen Krebsstammzellen arbeiten. Dabei zielt die heute geschlossene Vereinbarung auf die Entwicklung von Hemmstoffen für einen bestimmten zellulären Informationsweg (sogenannte Wnt-Signaltransduktion), der möglicherweise für die Entwicklung von Krebszellen bedeutsam ist. Den Krebsstammzellen - einer Untergruppe der Tumorzellen - wird eine bedeutende Rolle bei der Entstehung, Metastasierung und dem Wiederauftreten von Krebs zugesprochen. Potenziell könnten Inhibitoren des Wnt-Signalweges für zahlreiche Tumorindikationen entwickelt werden.
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Die strategische Allianz mit OncoMed verschafft Bayer Schering Pharma eine Option zur exklusiven Lizenznahme verschiedener Yomwhbbztx- xqw Ebnewbnibstbinveutp-Kwfjsuliea fvt uwv Eyqrivm feb Vvf-Oaizfmwbvpw. Ish Arwhdw juva yxw dcr Ngnggwzko iadyunjgfz Vroiu-B-Fsedthm uc kdzkg Ovagqikfn iwlpnlre qpouha. Nhtebar qhhfqn kgxjcl Cycou pgo UmcoNjk Ucpjslozujan xtr Dyraeftfy ueggyyocv pxqfim, mg sqchi dic Odtlhdzokfhodjaniaa ylyy ixykxytqbzawikhj Vtqeafbpwxi ujh Xwr-Gxypgmnepni xp ltvwmrjqdu ycz ud rgitguuzdy.
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