Bei Patienten mit einer frühen schubförmig remittierenden Multiplen Sklerose (RRMS), die einmal jährlich Alemtuzumab verabreicht bekamen, war das Schubrisiko um 74 Prozent und das Risiko einer dauerhaften Behinderung um 71 Prozent geringer als bei Vergleichspatienten, die mit Rebif® (hoch dosiertes Interferon beta-1a) behandelt wurden. Von besonderer Bedeutung ist dabei, dass sich der durchschnittliche Behinderungsgrad der Patienten unter der Alemtuzumab-Behandlung von Anfang an verbessert hat, während sich der Grad der Behinderung der Rebif-Patienten verschlechterte. Der Behandlungserfolg mit Alemtuzumab hielt mindestens drei Jahre lang an, obwohl die meisten der mit Alemtuzumab behandelten Patienten zwei Jahre zuvor die letzte Dosis erhalten hatten.
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