Präeklampsie, eine schwere Komplikation in der Schwangerschaft, ist eine der Haupttodesursachen für Mutter und Kind in Europa und den USA. Betroffen ist etwa jede 20. Schwangerschaft. Hauptsymptome sind Bluthochdruck und Eiweiß im Urin. Die Entstehung der Präeklampsie ist nach wie vor ungeklärt. Dr. Florian Herse (Experimental and Clinical Research Center, ECRC, von Max-Delbrück-Centrum, MDC, und Charité) sowie Dr. Ralf Dechend (ECRC und Helios Klinik Berlin) haben jetzt ein Enzym entdeckt, das bei betroffenen Frauen verstärkt auftritt und offenbar an der Symptomatik beteiligt ist. Im Tierversuch blockierten sie dieses Enzym und konnten so den Krankheitsverlauf mildern (10.1161/CIRCULATIONAHA.112.127340)*.
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